Monkeypox is a viral disease that is transmitted person to person through direct contact with the infectious rash, scabs or bodily fluids including respiratory secretions. Research is ongoing on the potential for sexual transmission through semen or vaginal fluids. Indirect transmission can occur through touching contaminated objects, like towels, bedsheets or sex toys. Most people with monkeypox recover on their own without requiring treatment, beyond supportive care or hospitalization. Due the similarity between monkeypox and smallpox, and because this virus has been found in humans for decades, FDA approved monkeypox tests, treatments (TPOXX), and vaccines exist, but their use has so far been very limited.