Although the truck-jacking of highly radioactive material outside Mexico City on December 1, 2013 ended without the worst case materializing, it should serve as a wakeup call, not just in Mexico but also in the United States and elsewhere. Dangerous radiation sources remain vulnerable to theft, especially when they are out on the road. There is also poorly protected radioactive material in hospitals and other facilities. Improving security requires tougher regulations and greater risk awareness in the industry. Unfortunately, the United States is no exception, so it’s time for the country to get serious about locking up its radioactive material.