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From Proliferation to Restraint: A Process-Based Approach to Artificial Intelligence and Weapons of Mass Destruction

Artificial intelligence (AI) is now a central element in many of the most pressing debates about nuclear, biological, and chemical weapons. Yet, the scholarship on AI and weapons of mass destruction (WMD) remains highly fragmented. Much of the existing literature asks whether AI may lower knowledge barriers to dangerous activities by increasing access to expertise or accelerating sensitive research. Another strand focuses specifically on nuclear weapons and the concerns that AI integration into command-and-control architecture could jeopardize strategic stability by compressing decision time or eroding meaningful human control. A third body of work turns to monitoring and verification, where AI may offer governments and open-source intelligence analysts new avenues to assess compliance and noncompliance with arms-control, nonproliferation, and disarmament obligations. Finally, a fourth set of studies zooms in on governance institutions and whether they can keep pace with private-sector technology before AI-enabled WMD risks emerge. This introduction argues that these conversations should not be siloed. It advances a process-based approach that tracks how AI may alter the pursuit, operationalization, detection, and eventual constraint of WMD capabilities. Developments at one stage of the life cycle can also affect what happens elsewhere. This overview illustrates just how rapidly AI is reshaping the entire spectrum of WMD politics.

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In April 2026, more than 100 experts from frontier laboratories, national governments, international organizations, and research institutions met in California for the first meeting of the Asilomar Process to discuss how AI is reshaping the risks presented by nuclear and biological weapons. Image: Eduardo Fujii.

Recommended citation

Herzog, Stephen. "From Proliferation to Restraint: A Process-Based Approach to Artificial Intelligence and Weapons of Mass Destruction." The Nonproliferation Review, Vol. 33, Nos. 1–3 (February–June 2026): 3–24.

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