Putin's Russia: How is the West Responding?

Russian President Vladimir Putin is warning the West. In his State of the Union address, he announced that he would react swiftly and harshly if provoked by other countries. Relations between Russia, the US, and the EU are strained, and there are several points of contention: the conflict in Eastern Ukraine and Putin's actions against his imprisoned critic, Alexei Navalny. 

How can the so-called East-West conflict be defused? What hope is there for normalization of the US-Russia relationship under President Joe Biden? [translated from German; interview in German]